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AAIPharma, Inc. ,Morrisville, North Carolina:Biotech Serive Company, pharmaceutics, analytical, bioanalytical, clinical, and regulatory services.

Aeolus Pharmaceuticals Corporation, Research Traingle Park, NC:Developing a new class of disease-modifying drugs. Aeolus compounds have demonstrated efficacy in preclinical models of amyotrophic lateral sclerosis (ALS) and cancer. Aeolus is currently conducting clinical trials in ALS.

Affinergy Inc., Durham, NC:Develops site-specific biological systems using biofriendly linkers that selectively adhere to proteins, drugs, cells, and biomaterial surfaces in order to kickstart biology toward an intended outcome. Affinergy is focused on developing coatings and medical devices for the orthopedic and cardiovascular markets. Affinergy's technology was patented at Duke University and was awarded 2005 Innovation of the Year by Frost & Sullivan in the category of Medical Device Coatings.

Ajinomoto AminoScience, Raleigh, NC:A wholly owned subsidiary of Ajinomoto Co., Inc. The Raleigh, NC plant has been in operation since 1982 and continues to be the only pharmaceutical L-amino acid manufacturer in the United States.

Aldagen, North Carolina, NC: Developing and commercializing proprietary products that improve the identification and selection of more effective adult stem cell populations. These highly unique stem cells have the potential to revolutionize treatments of cancer, cardiovascular disease and other degenerative diseases.

Alderon Biosciences, Durham, NC:P roduces diagnostic systems for medical, environmental, and laboratory research and testing needs. The company's novel electrochemical assay products are designed for the detection of metals (lead), peroxide, nucleic acids, proteins, and antigens.

AlphaVax LLC., Durham, NC:A vaccine development company whose core technology is a proprietary viral vector system that will support innovative new vaccines in a broad array of diseases, and which is in the clinical stage of its development.

Amplistar, Winston-Salem, NC:Provides blood testing services for the early detection of a wide variety of cancers, including colon, lung, prostate and breast cancers.

AQF Technologies, Charlotte, NC:A fully owned subsidiary of BBA Nonwovens, is a leader in the development, manufacturing, and marketing of specialty filtration material.

Archer Daniels Midland Company (ADM), Southport, NC:A world leader in agricultural processing. ADM is one of the world's largest processors of soybeans, corn, wheat and cocoa. ADM is also a leader in the production of soy meal and oil, ethanol, corn sweeteners and flour. In addition, ADM produces value-added food and feed ingredients. Headquartered in Decatur, Illinois, ADM has over 26,000 employees, more than 270 processing plants.

Ardent Pharmacautical, Inc., Durham, NC: Discovers and develops delta receptor compounds. As a private company it has developed a substantial knowledge of the chemistry and pharmacology of the delta receptor, including a library of approximately 1,000 compounds that demonstrate specific opiate receptor activity. Ardent has discovered and is developing compounds in moderate-to-severe pain, urinary incontinence, premature ejaculation, depression and cardioprotection. Development stages for these products range from pre-clinical target compound selection through to Phase 1.

Argos Therapeutics, Durham, NC:Formerly Merix Bioscience, is a pioneer in immunotherapy. Argos is developing the next generation of therapies in the areas of oncology, infectious diseases, autoimmune disorders and transplantation.

BD Technologies, Research Triangle Park, NC: BD (Becton, Dickinson and Company) is a medical technology company that serves healthcare institutions, life science researchers, clinical laboratories, industry and the general public. BD manufactures and sells a broad range of medical supplies, devices, laboratory equipment and diagnostic products.

BioAbility., Research Triangle Park, North Carolina: Market Research Company, Technology & Competitor Analysis, Competitive Surveillance Programs, Competitive Surveillance Program, Business Intelligence

Biogen Idec, Inc. (North Carolina) Research Triangle Park, NC: Biogen Idec is dedicated to pursuing the creativity of science. The company is products and development programs address a variety of key medical needs in the areas of oncology, neurology, dermatology and rheumatology.

Biolex, Inc., Pittsboro, North Carolina. Developing and commercializing therapeutic proteins based on its proprietary LEX System

SM

, an expression system that enables the production of hard-to-make proteins and the optimization of monoclonal antibodies.

BioResource International, Raleigh, NC:A biotechnology company focused on the discovery and development of enzymes to enhance and protect animal and human health.

BioStratum, Durham, NC:Focused on the discovery, development and commercialization of novel therapeutic agents for the treatment of diabetes and diabetic complications. BioStratum's pipeline is led by Pyridorin a small molecule drug for the treatment of diabetic kidney disease, followed by pre-clinical compounds that will treat other diabetic complications and cancer.

Biotechnics, Hillsborough, NC: A privately held company that provides high quality, cost-effective and timely histopathology and toxicology services in support of drug development and chemical safety assessment.

Boron Biologicals Inc., Raleigh, NC:Produces research samples of boronated amino acids, peptides, neurotransmitters and DNA.

Buxco Electronics, Inc. Wilmington, NC:

Cato Research, Durham, NC:A privately held contract research organization.
organization helping clients in the pharmaceutical, biotech and medical device industries obtain regulatory approval for their new products.

Cempra Pharmaceuticals, Morrisville, NC:A newly founded biotechnology company focused on anti-infectives. The company was founded by Prabhavathi Fernandes, Ph.D. who was the leading microbiologist for Clarithromycin development at Abbott. Cempra is committed to the development of best-in-class antibiotics to meet urgent and unmet needs to treat drug resistant bacteria.

Charles River Laboratories, Raleigh, NC:Based in Wilmington, Massachusetts, is a global provider of solutions that advance the drug discovery and development process.

Chimerix Inc., Durham, NC:Discovers, develops and commercializes therapeutics with enhanced pharmaceutical properties that are active against a broad range of viral diseases. Leveraging a powerful lipid, prodrug technology, ProLipTag™, Chimerix is able to develop drug candidates with oral-availability, increased potency and targeted delivery

Cirrus Pharmaceuticals, Inc., Research Triangle Park, NC: biotechnology and pharmaceutical, product development company, physical and chemical characterization, formulation development, stability testing, container/closure selection, process development, scale-up and technical transfer to manufacturing for inhaled, oral, topical and parenteral products.

Closure Medical, Raleigh, NC:Designs, develops, and manufactures a variety of biomaterial-based medical adhesives.

Cogent Neuroscience Inc., Durham, NC: A neurological target and drug discovery company that uses its Gene Rover technology platform to screen the human genome for functional gene targets that will serve as the basis for the discovery of new therapeutics for the treatment of stroke, brain injury, and neurodegenerative diseases like Alzheimer's Disease, ALS and Parkinson's Disease.

Covance, Research Triangle Park, NY:Headquarters in Princeton, New Jersey, is one of the world's largest and most comprehensive drug development services companies with annual revenues greater than $1 billion, global operations in 18 countries, and approximately 6,700 employees worldwide.

CRB Consulting Engineers, Inc.: Cary, NC: An international design firm specializing in facility and process design for high technology industries. Provides design of facilities for pharmaceutical, vaccine, contract, clinical, bioprocess manufacturings, clean room and fermentation suites.

Curacyte AG, Chaple Hill, NC: A research-based biopharmaceutical company dedicated to the discovery and development of innovative and clinically meaningful new medicines in the areas of hematology, antithrombosis and oncology.

D-Pharm is a biopharmaceutical company pioneering the development of lipid-like therapeutics. D-Pharm has generated a rich product pipeline from its drug targeting and drug discovery technologies, Regulated Activation of Prodrugs (D-RAPTM), Membrane Active Chelators (MAC), and LipidoMimetix. Currently, the company's business strategy is to continue to develop DP-b99 through to completion of Phase IIb and then to seek a partner for further development and commercialization. D-Pharm is actively seeking development partners for its other pipeline products, including DP-VPA, which has successfully completed a phase II study for epilepsy.

DevCo Pharmaceutical Inc., Durham, NC:Based in Guildford, United Kingdom, is a virtual pharmaceutical company focusing on neuroscience. DevCo has identified and acquired a number of licences to develop drug candidates, particularly in the field of neuroscience. Currently the Company has a total of six compounds in development. DevCo funds and manages the completion of the development whilst out-sourcing the operations to contract research organisations.

DSM Food Specialties, Charlotte, NC:A leading producer of value-added ingredient solutions for the international food, feed and beverage industries.

Embrex Inc., Durham, NC: A subsidiary of Pfizer, is an international agricultural biotechnology company focused on developing patented biological and mechanical products that improve bird health, reduce bird and production costs and provide other economic benefits to the poultry industry. The company has developed and commercialized the first in ovo platform delivery system called the Inovoject® system, a proprietary, automated, injection system which eliminates the need for manual vaccination of newly hatched broiler chicks.

EMD Pharmaceuticals, Inc., Durham, NC. EMD Pharmaceuticals focuses on meeting patient and physician needs with pioneering pharmaceutical products and services with an initial emphasis on launching new products in oncology.

Endeavor Pharmaceuticals, Wilmington, NC:A specialty pharmaceutical company focused on improving women's health by developing and marketing advanced hormone therapies. The Company is seeking to commercialize a portfolio of hormone replacement therapy product candidates that have been developed based on their proprietary, complex combination of multiple estrogens.

Eno River Labs, Durham, NC:A woman-owned small business in Durham, NC providing analytical services to both the environmental and biotech industries. Our environmental services include high quality analytical data for dioxin/furan and PCB analysis as well as custom research and development work using HRGC-LRMS, HRGC-HRMS or LC-MS/MS. Our bioanalytical services specialize in GLP and non-GLP analysis of small molecule drugs in biological matrices in support of pre-clinical through clinical studies in the drug development process. Our services include LC/MS/MS and GC/MS bioanalytical method development and validation.

EnSolve Biosystems, Inc., Raleigh, NC:Provides innovative, proprietary solutions to the maritime, industrial and consumer markets, using biotechnology.

Entegrion, Inc., Research Triangle Park, NC:Formed through the merger of Hemocellular Therapeutics located in North Carolina and ProFibrix located in Leiden, The Netherlands is focused on the development of drugs that stop bleeding.

Erimos Pharmaceuticals: Raleigh, NC.

Expression Analysis, Durham, NC:A market leader in microarray outsourcing, providing experimental design consultation, biologic sample preparation, sample processing and data/statistical analysis services to clients worldwide.

Flexcell® International Corporation, Hillsborough, NC:Specializes in designing and manufacturing products to service the Cytomechanics marketplace. Cytomechanics is the field of study involving cell responses to mechanical load.

Fortron Bioscience Inc., Morrisville, NC:One of the world's leading primary manufacturers of bulk quantities of purified antibody and antigen reagents.

Fresenius Kabi, Clayton, NC:The leader in infusion therapy and clinical nutrition in Europe and in its most important countries of Latin America and Asia Pacific.

Gene Tec Corporation, Durham, NC:Produces DNA-based testing equipment and automated gene-detection instruments.

GlaxoSmithKline, Research Triangle Park, NC: Pharmaceutical, treatments for asthma, HIV/AIDS, malaria, depression, migraine, diabetes, heart failure, digestive conditions and cancer. Market over 25 vaccines to protect against illnesses such as hepatitis A and B, diphtheria, tetanus, whooping cough, typhoid and influenza

Icagen, Inc. ,Durham, NC. Icagen is a biopharmaceutical company focused on the discovery, development and commercialization of novel orally-administered small molecule drugs that modulate ion channel targets. Utilizing its proprietary know-how and integrated scientific and drug development capabilities, Icagen has identified multiple drug candidates that modulate ion channels.

Icoria, Research Triangle Park, NC:(formerly Paradigm Genetics) is a biotechnology company applying its proprietary systems biology platform to the discovery of safer, more effective drugs and agrichemicals. Icoria has major collaborations with the National Institute of Environmental Health Sciences, Bayer CropScience, the Monsanto Company, Pioneer Hi-Bred International, the National Institute of Standards & Technology's Advanced Technology Program, and L'Oreal Inc.

IEP Pharmaceutical Devices, Inc. (IEP) as a wholly owned subsidiary of Aeropharm. The assets and intellectual property of IEP were acquired from IEP Group, Inc., a provider of device engineering and consultation services, principally for the medical device and pharmaceutical industries. Prior to the acquisition, IEP Group, Inc. had contributed to the development of several Kos Metered-dose inhalation (MDI) devices. As a Kos subsidiary, IEP will continue to develop proprietary technologies for the Company and will contribute to the Company's position as a full-scale aerosol development source, with expertise in device engineering, development and device manufacturing. Kos expects to leverage this full range of capabilities to establish future licensing, contract development, or joint venture

Inspire Pharmaceuticals, Inc:.Human Therapeutics. Inspire is a biopharmaceutical company dedicated to discovering, developing and commercializing novel prescription products for diseases with significant unmet medical needs. Inspire has significant technical and scientific expertise in the therapy areas of ophthalmology and respiratory and is a leader in the field of P2 receptors which are important drug targets in various therapeutic areas, including ophthalmology, respiratory disease, cardiovascular disease and pain. Inspire’s specialty sales force promotes Elestat™ and Restasis®, ophthalmology products developed by Inspire’s partner, Allergan, Inc.

Leiner Health Products, Wilson, NC: Generic Drug Maker. Full compliance with, the highest industry-recognized standards for Dietary Supplements.

MEDTOX Diagnostics, Burlington, NC:Operates a manufacturing plant for diagnostic drug screening devices. MEDTOX Diagnostics is a GMP, ISO-certified manufacturing facility that produces a variety of FDA-cleared drug screening devices for use in corporate, hospital, corrections and rehabilitation drug testing programs.

MorphoSys U.S. Inc., Charlotte, NC: A fully owned subsidiary of MorphoSys AG, Martinsried/Munich, Germany, develops and applies innovative technologies for the production of synthetic antibodies, which accelerate drug discovery and target characterization. The Company's proprietary Human Combinatorial Antibody Library (HuCAL®) technology is used by researchers worldwide for human antibody generation.

MWG Biotech Inc. High Point, NC: Genomics, Lab supplier, Molecular Biology. MWG Biotech Inc. USA, a subsidiary of MWG, Ebersberg, Germany, is a genomics solution that provides a variety of products and services for research needs from genome to gene function

NOBEX Corporation, Research Traingle Park, NC:A privately held drug product development company that specializes in medicinal chemistry applied to optimizing the delivery of therapeutic drugs by oral and other non-injectable routes of administration. The company has advanced three products into clinical study including; Oratonin, an oral modified salmon calcitonin with anti bone-resorptive and analgesic properties; the APAZA compound, an oral tablet for inflammatory bowel disease; and insulin in an oral tablet for diabetes. NOBEX has several other products in preclinical development on its own and with partners or collaborators including Pfizer, Duke University, and the Mayo Clinic.

Novartis Animal Health US, Greensboro, NC:A subsidiary of Novartis AG, researches, develops and commercializes leading animal treatments that meet the needs of pet owners, farmers and veterinarians.

Novo Nordisk Pharmaceutical Industries, Clayton, NC: Manufactures insulin products for individuals with diabetes. The products manufactured at the Clayton plant are marketed in North America, Europe, New Zealand and Australia.

Novozymes North America Inc. (NZNA), Franklinton, NC:Employs approximately 350 people and is the largest multi-purpose enzyme manufacturing plant in the United States. The site has departments that represent all business functions, including Production, Pilot Plant, Quality Control, Engineering, Sales, Tech Services, Marketing, Research & Development, Finance, Purchasing, Regulatory, Information Technology and Human Resources.

Nuada Pharmaceuticals, Durham, NC: Formerly ChemCodes, is a small molecule drug discovery company that has developed a proprietary high throughput medicinal chemistry discovery platform that provides benefits of quality, novel compound diversity and speed. ChemCodes is using its technology for internal clinical compound development and in collaborations with pharmaceutical and biotechnology companies to create enabling chemical synthesis solutions for the discovery and development of new medicinal compounds. The company currently is working on programs for proprietary internal drug development in the therapeutic areas of Cancer, Diabetes, and Inflammation.

Ockham Development Group, Cary, NC:Provides a wide range of consulting services through each step of the drug development supply chain whether through Ockham’s own service offering or through its valuable relationships across the biotech/pharmaceutical industry.

PAREXEL Consulting, Durham, NC:Provides a broad range of knowledge-based contract research, medical marketing and consulting services to the worldwide pharmaceutical, biotechnology and medical device industries

PharmaCore®, Inc.High Point, NC:Drug Discovery, Biotechnology

PharmaNetics, Raleigh, NC:A holding company incorporated in North Carolina as the parent company of Cardiovascular Diagnostics, Inc. Prior to ceasing substantially all of its operations in March 2004, PharmaNetics developed, manufactured and marketed rapid diagnostics to dose, manage and screen patients on drugs affecting coagulation.

PhytoMyco Research Corporation (PMRC), Greenville, NC:Provides novel plant and microbial extracts for discovery, development and commercialization. PMRC has 6000 novel plant extracts in vials and 96-well plates. Plates contain 80 samples each and with either 100 or 1000µg of material. The library is available for pharmaceutical and other screening needs on a non-exclusive basis.

Plureon Corporation, winston-Salem, NC:A privately owned biotechnology company that develop technologies originating at the Laboratory for Cell Therapy and Tissue Engineering of Children’s Hospital Boston, a teaching affiliate of Harvard Medical School.

POZEN Inc., Chapel Hill, NC:A pharmaceutical company committed to developing therapeutic advancements for diseases with unmet medical needs where it can improve efficacy, safety, and/or patient convenience. POZEN is focused primarily on the development of pharmaceutical products for the treatment of migraine. POZEN is also exploring the development of product candidates in other pain-related therapeutic areas. POZEN has development and commercial alliances with GlaxoSmithKline, Xcel Pharmaceuticals, and Nycomed.

PPD Piedmont Research Center, Morrisville, NC: Research, Human Therapeutics

PPD, Inc.,Wilmington, NC:Clinical Research. PPD is a leading global contract research organization providing discovery, development and post-approval services as well as compound partnering programs. Our clients and partners include pharmaceutical, biotechnology, medical device, academic and government organizations. With offices in 27 countries and more than 8,400 professionals worldwide, PPD applies innovative technologies, therapeutic expertise and a commitment to quality to help its clients and partners maximize returns on their R&D investments and accelerate the delivery of safe and effective therapeutics to patients.

Quintiles Transnational Corp., Durham, NC:Contract Services, Clinical Research

Rho, Inc., Chapel Hill, NC:Conctract Research Organization, Clinical Research

Ribonomics, Inc., Durham, NC: A systems biology company focused on the development of innovative products for the diagnosis and treatment of human diseases. Employing proprietary technologies developed at Duke University Medical Center, the Company empirically connects biological pathways to human disease. This capability represents a powerful solution for accelerating drug discovery.

Ryscor Science, Inc., Raleigh, NC: Develops novel small-molecule synthetic reagents and methodologies for pharmaceutical and biotechnology companies worldwide. The company's technology is focused on biologically-biased multifunctional molecules for diversity and target-oriented synthesis, enabling researchers involved in drug discovery to rapidly and reliably access target molecules. Ryscor's own research and development efforts are focused on breakthrough innovation in all major areas of biological discovery including pharmaceuticals, proteomics, genomics, and diagnostics.

Salix Pharmaceuticals, Raleigh, NC: Develops and markets prescription pharmaceutical products for the treatment of gastrointestinal diseases. Salix's strategy is to in-license late-stage or marketed proprietary therapeutic drugs, complete any required development and regulatory submission of these products, and market them through the Company's 100-member gastroenterology specialty sales and marketing team.

Schwarz Biosciences, Reseach Triangle Park, NC:US subsidiary of Schwarz Pharma AG of Monheim, Germany, develops and markets innovative drugs for unmet medical needs with focus on neurology, urology and cardiovascular diseases is developing projects targeting diseases such as Parkinson's disease, Restless Legs Syndrome, epilepsy, neuropathic pain and overactive bladder syndrome. The company has a strong international presence with subsidiaries in Europe, USA and Asia. Shares of SCHWARZ PHARMA AG are traded on the Frankfurt and Duesseldorf stock exchanges.

SCYNEXIS, Research Triangle Park, North Carolina with European operations, SCYNEXIS Europe Ltd., located near Cambridge, England. By combining its chemists' expertise with its proprietary MEDCHEM-FACTORY technology and Hit Explorer Operating System (HEOS®), SCYNEXIS is increasing the productivity and speed of the pharmaceutical discovery process. As an innovator in the field of high-speed synthesis with special expertise in the area of automation, SCYNEXIS is reshaping the process of discovery and optimization of new, promising chemical compounds.

Serenex Inc., Durham,NC:An integrated drug discovery and development company committed to improving the lives of patients by developing best-in-class therapeutic and supportive care products. Serenex has two best-in-class oncology-focused clinical stage programs. SNX-1012 is a product for chemotherapy and radiation-induced oral mucositis in solid tumor patients which is scheduled to complete phase 2 in late 2007. SNX-5422 is a novel, orally bioavailable, small molecule inhibitor of Heat Shock Protein 90. SNX-5422 is currently in phase 1 in cancer patients. Serenex’s pipeline is powered by a proprietary high throughput screening platform which enables the company to profile compounds, en masse, against thousands of important therapeutic and toxicity targets.

Serotec, Raleigh, NC: Headquarters are situated in Oxford, UK, supplies a comprehensive range of high quality immunological and cell biology reagents.

Specialty Operations Solutions, Inc. Research Triangle Park, NC:Leading supplier of research and laboratory services, regulatory compliance.

Sterigenics International, Charlotte, NC:World's leading provider of sterilization and ionization services for the healthcare, food safety and advanced appplications industries.

Stovall Life Science, Greensboro, NC:Designs, manufactures and markets laboratory instruments for the life sciences.

Synergy Vaccines, Research Triangle Park, NC:A biopharmaceutical company engaged in the research, development, and commercialization of novel vaccines using SynerVax adjuvant technology in order to provide more effective and less costly vaccines.

Syngenta biopharma, Research Triangle Park, NC:A business development unit of Syngenta, a world-leading agribusiness. It has an knowledgeable and dedicated team of professionals who are building on years of experience in plant biotechnology, bio-safety, pre-clinical and regulatory affairs to fully realize the potential of biopharmaceuticals.

Synthonix Corporation, Raleigh, NC: A subsidiary of Ryscor Science, specializes in small molecule heterocycles and synthons designed with biological and pharmacological use tailored to participate in proven chemical reactions such as Horner-Wadsworth-Emmons coupling, Suzuki coupling, Ugi reactions, condensations, cycloadditions, and many others.

Takeda Chemical Industries Limited, Wilmington, NC: is involved in the production and sales of chemical products such as drugs, medicine, research and general health care products. They also manufacture food products, products for use in the catering industry, bulk vitamins and beverages, chemical products, agricultural chemicals, animal health products, and environmental products. Takedo is the largest pharmaceutical company in Japan.

Targacept, Inc. Winston-Salem, NC:A biopharmaceutical company engaged in the design, discovery and development of drugs to treat multiple nervous system diseases and disorders by selectively targeting a class of receptors known as neuronal nicotinic acetylcholine receptors, or NNRs.

Touch Scientific Inc, Raleigh, NC:Created an analytical tear chemistry system in an accurate, fast, and convenient format for ophthalmic market.

TransTech Pharma, High Point, NC:A drug discovery company. They have developed and implemented a proprietary and efficient drug discovery engine called TTP Translational Technology®. This technology platform utilizes and translates genomic and proteomic data into safe and effective small molecule therapeutics in high throughput fashion, bypassing most of the classical requirements and bottlenecks in drug discovery.

Triangle Pharmaceuticals, Inc. Durham, NC: Building a specialty pharmaceutical company dedicated to developing effective solutions for serious viral disease, with a particular focus on therapies for the human immunodeficiency virus (HIV), including the acquired immunodeficiency syndrome (AIDS) and the hepatitis B virus (HBV).

TriE Medical Inc.,, Morrisville, NC:works with large or emerging organizations to provide product development services to the highly regulated healthcare industry. TriE develops products along any stage in the development process from conception to PMA or 510K submissions.

Trimeris Inc., Durham, NC:A biopharmaceutical company based in Durham, North Carolina. The company is engaged in the discovery and development of new drugs for the treatment of viral diseases. Our core technology platform focuses on compounds that inhibit viral replication by blocking viral fusion with healthy immune cells.

TriPath Imaging, Burlington, NC: formed by the merger of AutoCyte and NeoPath, develops, manufactures, markets and sells innovative solutions to improve the clinical management of cancer, including detection, diagnosis, staging and treatment. TriPath Oncology, a wholly owned subsidiary of TriPath Imaging, develops molecular diagnostic and pharmacogenomic products and services for malignant melanoma and cancers of the cervix, breast, ovary and prostate.

United Therapeutics, Research Triangle Park, NC:A biotechnology company focused on developing chronic therapies for life threatening conditions in three therapeutic areas: cardiovascular, oncology and infectious diseases.

Vascular Genetics, Durham, NC:A subsidiary of Corautus Genetics, is pursuing the development and commercialization of gene therapy products for the treatment of vascular diseases.

XDS, Durham, NC: has developed a bioassay that contains mammalian cell lines genetically engineered to contain the gene for luciferase, an enzyme fireflies use to produce light. In the patented CALUX® process, firefly luciferase is produced when dioxin-like chemicals are present. The process provides detection of dioxin and dioxin-like compounds at detection levels below one part per trillion, and is 40% to 70% less expensive than traditional analyses.

Zen-Bio, Inc., Research Triangle Park, NC:Involved in human adipocyte biology. The company has developed a technique for isolating and culturing human adipocytes (fat cells). Its mission is to provide the highest quality cells, reagents and contract services relating to adipocyte biology to the biomedical research community; to develop and commercialize research tools; and to leverage their expertise in this field into treatments for metabolic diseases through research and development and strategic alliances.